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Longevity biotech

Pilotmomentum 45902 papers in 3 months (+26% yearly)$1.1B raised in 12 months22 companies

Drugs and therapies that target the biology of aging itself to delay or reverse age-related decline and disease.

Why pilot: Life Biosciences dosed the first patient with ER-100, a partial epigenetic reprogramming therapy, in a Phase 1 trial. Jun 9, 2026

Papers per monthOpenAlex journal and conference papers; January includes papers dated by year only; the last two months are still filling in
0196392Sep 24Mar 25Sep 25Mar 26

Dots under a month: dated events tracked here that month.

26 events

DateEvent
Sep 2026
Sep 16Loyal's large-dog lifespan drug LOY-003 earns FDA RXEloyal.com· Milestone
Sep 7Rentosertib trial data read out on six proteomic aging clocksdoi.org· Breakthrough
Aug 2026
Aug 11XPRIZE Healthspan advances 20 finalist teamsxprize.org· Announcement
Jun 2026
Jun 9First patient dosed with partial reprogramming therapy ER-100lifebiosciences.com· Milestone
May 2026
May 21Calico and Nexo Therapeutics sign small molecule discovery dealcalicolabs.com· Deal
Feb 2026
Feb 24ARPA-H funds seven teams under PROSPRarpa-h.gov· Funding
Jan 2026
Jan 28FDA clears IND for Life Biosciences' reprogramming therapy ER-100lifebiosciences.com· Milestone
Jan 13FDA accepts safety section for Loyal's LOY-002loyal.com· Milestone
Dec 2025
Dec 4BioAge reports interim Phase 1 data for NLRP3 inhibitor BGE-102sec.gov· Milestone
Nov 2025
Nov 12AbbVie ends its decade-long partnership with Calicostatnews.com· Deal
Sep 2025
Sep 18Unity Biotechnology stockholders approve dissolutionsec.gov· Announcement
Aug 2025
Aug 14Altos Labs reports mesenchymal drift reversed by partial reprogrammingdoi.org· Breakthrough
Jul 2025
Jul 14Loyal completes enrollment of the STAY study at 1,300 dogsloyal.com· Milestone
Jun 2025
Jun 26Calico licenses Mabwell's IL-11 antibody for age-related diseasecalicolabs.com· Deal
Jun 9Shift Bioscience reports single-gene target for safer cell rejuvenationshiftbioscience.com· Breakthrough
Jun 3Nature Medicine publishes Phase 2a trial of AI-discovered drug rentosertibdoi.org· Breakthrough
May 2025
May 12XPRIZE Healthspan names first milestone winnersxprize.org· Announcement
May 2Unity Biotechnology cuts all staff after ASPIRE datasec.gov· Announcement
Apr 2025
Apr 22Senolytic UBX1325 results for diabetic macular edema publisheddoi.org· Breakthrough
Apr 14Loyal's STAY study enrolls 1,000 dogsloyal.com· Milestone
Feb 2025
Feb 26FDA accepts efficacy case for Loyal's senior dog lifespan drugloyal.com· Milestone
Jan 2025
Jan 6Calico's fosigotifator misses its goal in the HEALEY ALS platform trialcalicolabs.com· Milestone
Dec 2024
Dec 19ARPA-H launches the PROSPR healthspan programarpa-h.gov· Policy
Nov 2024
Nov 12Insilico reports positive Phase 2a results for its AI-designed IPF druginsilico.com· Milestone
Sep 2024
Sep 26BioAge Labs prices its Nasdaq IPOsec.gov· Deal
Feb 2024
Feb 1Loyal doses the first dog in its LOY-002 pivotal lifespan studyloyal.com· Milestone
About longevity biotech here
Sub-areas
Partial epigenetic reprogramming, Senolytics and senescence, Autophagy and metabolic aging, Aging clocks and biomarkers, AI-driven aging drug discovery, Cell therapy and iPSC rejuvenation, Veterinary longevity drugs
Stage evidence
Pilot, Jun 9, 2026: Life Biosciences dosed the first patient with ER-100, a partial epigenetic reprogramming therapy, in a Phase 1 trial. lifebiosciences.com
Momentum
45 of 100: the mean of its ranks among the tracked fields for paper growth (63), funding in 12 months (38) and events in 90 days (34). Method
Papers
3,417 in the 12 months ending two months ago, +26% against the 12 before (OpenAlex topics, journal and conference papers).
Tracked here since
Sep 25, 2026

Changes to this field

DateChange
Sep 25, 2026Longevity biotechTechnology: Added

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